I think is not possible to access directly to an Informix and dataverse databases directly from Appian Cloud but do you know if is there any work around?
Thanks in advance.
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As per your title, you need to setup a connected system/Integration to achieve this. Suggest you to connect with the respective team and get relevant connection details and setup a connected system.
No Direct connection possible,Expose the databases via REST API middleware, then connect Appian to that API using Connected Systems or integrations.