When does Appian at RunTime give a blank screen with just the UI elements being

This usually indicates you are using a query rule that points to a data store in your form for which the basic user doesn't have permissions over. This would be the case if you confirm that a System Administrator DOES NOT experience the issue.

If System Administrator accounts also experience the issue, then it means you have an invalid expression in your form.

In both cases, and as in any issue, you should always review the application-server.log.

Thanks Eduardo! As always your suggestion was helpful. Had used a CDT string to hold a User value which caused the issue.