In Integration side, While Fetching Integration Data Some times we get Timed Out connection , we should loop in expression rule until status code gets 200 without using process model , we should achieve in expression rule

No. Why not just increase the timeout?

But every time you iterate thorugh that integration in the expression rule, you'll end up firing that integration again and restarting again. I don't think it would help. Stefan's idea is better unless you have a reason not to follow that.